HPMA-RGD Hydrogels Seeded with Mesenchymal Stem Cells Improve Functional Outcome in Chronic Spinal Cord Injury

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F10%3A6788" target="_blank" >RIV/00064203:_____/10:6788 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/10:6788 RIV/68378041:_____/10:00348921 RIV/61389013:_____/10:00348921 RIV/00023001:_____/10:00002344
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
HPMA-RGD Hydrogels Seeded with Mesenchymal Stem Cells Improve Functional Outcome in Chronic Spinal Cord Injury
Original language description
In the paper the authors evaluate implantation of hydrogels based on hydroxypropylmethacrylamide with attached amino acids (HPMA-RGD) seeded with mesenchymal stem cells (MSCs; therapy group I) in the therapy of experimental chronic spinal cord injury (SCI) in rats. They compare this therapy with either implantation of HPMA-RGD hydrogels (therapy group II) or SCI only (control group). The results show that implantation of HPMA-RGD hydrogels seeded with MSCs led to improved motor and sensory function of the hindlimbs of the rats and reduced atrophy of the spinal cord after 6 months.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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