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An Electrophysiological Study of Visual Processing in Spinocerebellar Ataxia Type 2 (SCA2)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A6952" target="_blank" >RIV/00064203:_____/11:6952 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/11:10082228 RIV/00216208:11130/11:6952 RIV/00179906:_____/11:10082228

  • Result on the web

    <a href="http://www.ncbi.nlm.nih.gov/pubmed/20927662" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/20927662</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    An Electrophysiological Study of Visual Processing in Spinocerebellar Ataxia Type 2 (SCA2)

  • Original language description

    Reports of visual functional impairment in spinocerebellar ataxia type 2 (SCA2) have been studied previously using pattern reversal visually evoked potentials (VEPs) with contradictory results. To provide additional evidence to this area, visual functions were studied using VEPs and event-related potentials (ERPs) in a group of ten patients with genetically verified SCA2. The electrophysiological examination included pattern reversal and motion-onset VEPs as well as visually driven oddball ERPs with anevaluation of a target and a pre-attentive response. In six patients, we found abnormal visual/cognitive processing that differed from normal values in latency, but not in the amplitude of the dominant VEP/ERP peaks. Among the VEPs/ERPs used, the motion-onset VEPs exhibited the highest sensitivity and showed a strong Spearman correlation to SCA2 duration (from r = 0.82 to r = 0.90, p < 0.001) and clinical state assessed by Brief Ataxia Rating Scale (from r = 0.71 (p = 0.022) to r = 0.80

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA309%2F09%2F0869" target="_blank" >GA309/09/0869: Pre-attentional processing of visual information in man: electrophysiological study</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cerebellum

  • ISSN

    1473-4222

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    32-42

  • UT code for WoS article

    000287330600005

  • EID of the result in the Scopus database