Impairment of nasal mucociliary clearance in former smokers with stable chronic obstructive pulmonary disease relates to the presence of a chronic bronchitis phenotype

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7137" target="_blank" >RIV/00064203:_____/11:7137 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/11:7137 RIV/00216208:11150/11:10104092 RIV/00179906:_____/11:10104092

Result on the web

<a href="http://www.ncbi.nlm.nih.gov/pubmed/21991564" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21991564</a>

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Impairment of nasal mucociliary clearance in former smokers with stable chronic obstructive pulmonary disease relates to the presence of a chronic bronchitis phenotype

Original language description

Background: Associations between nasal and bronchial impairment have been repeatedly described in chronic obstructive pulmonary disease (COPD), whereas nasal mucociliary clearance (MCC) in COPD patients is not yet fully understood. We studied nasal MCC parameters in COPD patients and compared them with healthy adults (HA) and with cystic fibrosis (CF) patients with compromised MCC. Methodology: An observational study of 98 COPD ex-smokers and subjects from control groups evaluated for nasal MCC time (NMCCt) and by digital video microscopy of nasal mucosa recording ciliary beat frequency (CBF) and ciliary beat pattern. Results: The NMCCt was decreased in HA compared to those with COPD and decreased in those with COPD compared to those with CF. CBF in COPD was lower compared to HA. The index of ciliary dyskinesia in COPD patients differed from HA. We detected higher NMCCt and lower nasal CBF in patients with chronic bronchitis phenotype (CB) compared to non-CB patients. Conclusions: We c

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FC - Pneumology

OECD FORD branch

—

Project

<a href="/en/project/NR8407" target="_blank" >NR8407: Functional and ultrastructural examination of respiratory cilia in adult patients suffering from chronic obstructive pulmonary disease.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Rhinology

ISSN

0300-0729

e-ISSN

—

Volume of the periodical

49

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

10

Pages from-to

397-406

UT code for WoS article

000297454100004

EID of the result in the Scopus database

—