Antiepileptic drug interactions: A clinical case demonstration

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7239" target="_blank" >RIV/00064203:_____/11:7239 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/11:7239

Result on the web

<a href="http://www.medvik.cz/link/bmc11034501" target="_blank" >http://www.medvik.cz/link/bmc11034501</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Antiepileptic drug interactions: A clinical case demonstration

Original language description

Epilepsy is a serious health disorder affecting both paediatric and adult population worldwide. Due to difficulties in identifying its aetiology, initial management is often guided by empiric therapy measures. Symptomatic control requires the use of antiepileptic drugs (AEDs), many of which have the potential for adverse drug interactions. Children are especially susceptible to drug interactions and frequently exhibit atypical adverse events, which may require special care. Aim. To demonstrate a case ofa 15 year old girl suffering from refractory epilepsy with underlying focal cortical dysplasia (FCD), whose seizure deterioration was most probably associated with drug-drug interactions between prescribed common antiepileptic drugs, namely valproic acid, phenobarbital or the prodrug primidon and carbamazepine.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Časopis lékařů českých

ISSN

0008-7335

e-ISSN

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Volume of the periodical

150

Issue of the periodical within the volume

8

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

451-456

UT code for WoS article

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EID of the result in the Scopus database

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