Status Epilepticus Associated With the Administration of Long-Acting Methylphenidate in a 7-Year-Old Girl

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F12%3A8029" target="_blank" >RIV/00064203:_____/12:8029 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/12:8029
Result on the web
<a href="http://dx.doi.org/10.1097/JCP.0b013e3182499a16" target="_blank" >http://dx.doi.org/10.1097/JCP.0b013e3182499a16</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Status Epilepticus Associated With the Administration of Long-Acting Methylphenidate in a 7-Year-Old Girl
Original language description
Children with attention-deficit/hyperactivity disorder (ADHD) may be at elevated risk for seizures.1 Stimulant therapy, commonly used to treat ADHD, may lower seizure threshold.2 However, few studies address whether psychostimulants contribute to de novoseizures or exacerbate seizure disorders. Relevant safety data are limited because patients with epilepsy are typically excluded from clinical trials.3 Evidence suggests that methylphenidate (MPH) administration might increase or decrease seizure frequency in patients with epilepsy.2 We present the case of a child with severe ADHD and unidentified cortical malformation who developed status epilepticus while treated with osmotic release oral system (OROS) MPH and immediate release (IR) MPH. Her parentsdocumented permission to allow this report.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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