Uncommon leukemic case of anaplastic large cell lymphoma diagnosed through a typical chromosomal abnormality t(2;5) with a null phenotype and aberrant expression of NG2 and CD13
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F12%3A8189" target="_blank" >RIV/00064203:_____/12:8189 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/12:8189
Result on the web
<a href="http://dx.doi.org/10.4149/BLL_2012_091" target="_blank" >http://dx.doi.org/10.4149/BLL_2012_091</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Uncommon leukemic case of anaplastic large cell lymphoma diagnosed through a typical chromosomal abnormality t(2;5) with a null phenotype and aberrant expression of NG2 and CD13
Original language description
Anaplastic large cell lymphoma represents approximately 10-15 % of pediatric non-Hodgkin lymphomas. Leukemic presentation is very rare, and in particular, the null phenotype ALCL without typical anaplastic morphology together with aberrant expression ofCD13 and/or CD11b represents a diagnostic challenge. We report a case of a 9 year-old boy with leukemic presentation of ALCL with the typical translocation t(2;5) (p23;q35); in this patient, the only positive antigens identified by immunophenotyping wereCD13, NG2 HLA-DR, and CD38. To our knowledge, aberrant expression of NG2 has never been reported in ALCL cases.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislava Medical Journal - Bratislavské Lekárske listy
ISSN
0006-9248
e-ISSN
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Volume of the periodical
113
Issue of the periodical within the volume
7
Country of publishing house
SK - SLOVAKIA
Number of pages
5
Pages from-to
404-408
UT code for WoS article
000306941100003
EID of the result in the Scopus database
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