Lactic acidosis in medical ICU - the role of diabetes mellitus and metformin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F12%3A8892" target="_blank" >RIV/00064203:_____/12:8892 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/12:8892

Result on the web

<a href="http://www.ncbi.nlm.nih.gov/pubmed/23391971" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/23391971</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Lactic acidosis in medical ICU - the role of diabetes mellitus and metformin

Original language description

OBJECTIVES: To evaluate the significance of diabetes mellitus and metformin in patients admitted to medical ICU with lactic acidosis. METHODS: All the patients admitted to medical ICU with serum lactic acid exceeding 5 mmol/L and pH<7.35 were enrolled into analysis. The impact of diabetes mellitus and metformin treatment on ICU presence of lactic acidosis and its mortality was evaluated. The metabolic parameters were compared with respect to the presence of diabetes mellitus and metformin application. RESULTS: Lactic acidosis was detected in 69 (4%) out of 1,755 admitted patients, 44 were nondiabetic and 25 had diabetes mellitus, 11 of them treated with metformin. No significant impact of diabetes mellitus or metformin application on presence of lacticacidosis and its mortality was detected. In nondiabetic subjects mortality was associated with eGFR and the presence of acute renal failure while in diabetic patients with sepsis. Acute renal failure was detected in 9 out of 11 patients

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

8

Country of publishing house

SE - SWEDEN

Number of pages

4

Pages from-to

792-795

UT code for WoS article

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EID of the result in the Scopus database

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