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Predictors of seizure-free outcome after epilepsy surgery for pediatric tuberous sclerosis complex

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F13%3A10196671" target="_blank" >RIV/00064203:_____/13:10196671 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/13:10196671 RIV/68407700:21230/13:00208529

  • Result on the web

    <a href="http://dx.doi.org/10.1111/epi.12371" target="_blank" >http://dx.doi.org/10.1111/epi.12371</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/epi.12371" target="_blank" >10.1111/epi.12371</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Predictors of seizure-free outcome after epilepsy surgery for pediatric tuberous sclerosis complex

  • Original language description

    PurposeVariable predictors of postsurgical seizure outcome have been reported in children with tuberous sclerosis complex (TSC). We analyzed a large surgical series of pediatric TSC patients in order to identify prognostic factors crucial for selection of subjects for epilepsy surgery. MethodsThirty-three children with TSC who underwent excisional epilepsy surgery at Miami Children's Hospital were retrospectively reviewed. A total of 29 clinical, neuropsychological, electroencephalography (EEG), magnetic resonance imaging (MRI), and surgical variables were analyzed and related to seizure outcomes. Univariate Barnard's exact test, Wilcoxon's rank-sum test, and multivariate statistical Cox's model were used to examine the significance of associations between the variables and seizure outcome. Key FindingsEighteen patients (55%) have been seizure-free 2years after (final) surgery; postoperative complications occurred in five subjects (15%). Complete removal of epileptogenic tissue detecte

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT13357" target="_blank" >NT13357: Defining epileptogenicity markers in tuberous sclerosis and improvement in epilepsy surgery</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Epilepsia

  • ISSN

    0013-9580

  • e-ISSN

  • Volume of the periodical

    54

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1913-1921

  • UT code for WoS article

    000326551300012

  • EID of the result in the Scopus database