Prevalence and treatment of anti-NMDA receptor encephalitis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F13%3A10209568" target="_blank" >RIV/00064203:_____/13:10209568 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/13:10209568

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S147444221370070X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S147444221370070X</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Prevalence and treatment of anti-NMDA receptor encephalitis

Original language description

We have been treating an 8-year-old girl with anti-NMDAR encephalitis for more than 1 year. The disease manifested with movement disorder mimicking polyradiculomyelitis. During the first week of hospital admission, the girl received intravenous immunoglobulin with no clinical response. Within 3 weeks, she developed deep coma with autonomic instability. Her serum and CSF were positive for anti-NMDAR antibodies. Plasma exchange and high-dose corticosteroids were immediately applied, followed by rituximab,with no effect. Therefore, cyclophosphamide treatment was started of which she received seven cycles. Three cycles stabilised her autonomic system, but she developed intractable motor restlessness and remained in coma. Four subsequent cycles were strengthened by removal of antibodies from peripheral blood with immunoadsorptions; nevertheless, the girl's neurological status remained unchanged.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Lancet Neurology

ISSN

1474-4422

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

2

Pages from-to

424-425

UT code for WoS article

000318836700010

EID of the result in the Scopus database

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