Impact of histological variants ononcological outcomes of patients with urothelial carcinoma of the bladder treated with radical cystectomy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F13%3A10209659" target="_blank" >RIV/00064203:_____/13:10209659 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/13:10209659

Result on the web

<a href="http://dx.doi.org/10.1016/j.ejca.2013.02.001" target="_blank" >http://dx.doi.org/10.1016/j.ejca.2013.02.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejca.2013.02.001" target="_blank" >10.1016/j.ejca.2013.02.001</a>

Result language

angličtina

Original language name

Impact of histological variants ononcological outcomes of patients with urothelial carcinoma of the bladder treated with radical cystectomy

Original language description

Objective: To investigate the impact of variant histologies of urothelial carcinoma of the bladder (UCB) on oncologic outcomes after radical cystectomy (RC). Materials and Methods: Data from 1984 UCB patients treated by RC without preoperative chemo-or radiotherapy were reviewed for histological differentiation and variants. We analysed the differences between pure UCB and UCB with variant histology, and those between the different histological variants using various stratifications. Results: Overall, 488 (24.6%) patients had UCB variants with squamous cell (11.4%) and glandular differentiation (3.8%) being the most common. Histological UCB variants were associated with advanced tumour stage, lymphovascular invasion and lymph node metastasis (all p-values <0.01) when compared to pure UCB. In univariable analyses, patients with non-squamous UCB variants were at significantly higher risk for disease recurrence and cancer-specific mortality than those with pure UCB patients (p-values = 0.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Cancer

ISSN

0959-8049

e-ISSN

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Volume of the periodical

49

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

1889-1897

UT code for WoS article

000318610500011

EID of the result in the Scopus database

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