Effect of Rosuvastatin Therapy on Troponin I Release Following Percutaneous Coronary Intervention in Nonemergency Patients (from the TIP 3 Study)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10227340" target="_blank" >RIV/00064203:_____/14:10227340 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/14:10227340 RIV/00216208:11140/14:10227340 RIV/00669806:_____/14:10227340 RIV/00216224:14110/14:00081970
Result on the web
<a href="http://dx.doi.org/10.1016/j.amjcard.2013.10.026" target="_blank" >http://dx.doi.org/10.1016/j.amjcard.2013.10.026</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.amjcard.2013.10.026" target="_blank" >10.1016/j.amjcard.2013.10.026</a>

Result language
angličtina
Original language name
Effect of Rosuvastatin Therapy on Troponin I Release Following Percutaneous Coronary Intervention in Nonemergency Patients (from the TIP 3 Study)
Original language description
Several randomized studies have suggested that pretreatment with statins may reduce a periprocedural biomarker release in patients who underwent percutaneous coronary intervention (PCI); however, results remain controversial. The purpose of this study was to investigate the effect of a 1-day rosuvastatin therapy on troponin I release in patients who underwent nonemergency PCI. A total of 445 patients with angina pectoris were randomly assigned to therapy with rosuvastatin (20 mg 12 hours before coronaryangiography + 20 mg immediately before PCI; rosuvastatin group, 220 patients) or PCI without statin therapy (control group, 225 patients). In patients taking statins (73%), rosuvastatin was added to their long-term statin therapy. The primary end pointwas the incidence of TnI microleak defined as TnI elevation >1.5 x upper limit of normal, and the secondary end point was the incidence of post-PCI TnI elevation >3 x upper limit of normal. The incidence of primary and secondary end point
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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