The use of early postoperative prostate-specific antigen to stratify risk in patients with positive surgical margins after radical prostatectomy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10293072" target="_blank" >RIV/00064203:_____/14:10293072 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/14:10293072
Result on the web
<a href="http://dx.doi.org/10.1186/1471-2490-14-79" target="_blank" >http://dx.doi.org/10.1186/1471-2490-14-79</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1471-2490-14-79" target="_blank" >10.1186/1471-2490-14-79</a>
Alternative languages
Result language
angličtina
Original language name
The use of early postoperative prostate-specific antigen to stratify risk in patients with positive surgical margins after radical prostatectomy
Original language description
Background: It is well recognized that the presence of positive surgical margins (PSM) after radical prostatectomy (RP) adversely affects cancer specific outcomes and recent evidence from randomized trials supports the use of adjuvant radiotherapy in these cases. However, not all of the patients with PSM develop disease recurrence and the policy of adjuvant radiation could result in considerable over-treatment. We investigated the ability of early postoperative prostate specific antigen (PSA) and PSA decline rates to stratify the risk of disease progression during the first weeks after the surgery thereby allowing adequate time for planning eventual adjuvant therapy. Methods: We studied 116 consecutive patients with the finding of PSM after RP for localized prostate cancer between 2001 and 2012. No patients were treated with radiation or hormonal therapy. An intensive postoperative PSA monitoring using ultrasensitive assay started first at day 14 after the surgery, then at day 30, 60,
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Urology
ISSN
1471-2490
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
neuveden
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
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UT code for WoS article
000345463700001
EID of the result in the Scopus database
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