Treatment of lower extremity superficial vein thrombosis with low molecular weight heparin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332609" target="_blank" >RIV/00064203:_____/16:10332609 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/16:10332609

Result on the web

<a href="http://dx.doi.org/10.4149/BLL_2016_115" target="_blank" >http://dx.doi.org/10.4149/BLL_2016_115</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2016_115" target="_blank" >10.4149/BLL_2016_115</a>

Result language

angličtina

Original language name

Treatment of lower extremity superficial vein thrombosis with low molecular weight heparin

Original language description

AIM: The aim of our study was to ascertain the efficacy of low-molecular-weight heparin (LMWH) in the treatment of patients with SVT. MATERIAL AND METHODS: A group of 336 outpatients with clinical diagnosis of SVT was evaluated in this prospective study. At the beginning of the study all patients were examined by clinical investigation, laboratory tests and duplex ultrasound investigation (examination). All patients included into the study were treated with LMWH. Clinical and ultrasound evaluation was carried out on days 10, 30 and 90 of the follow-up. This clinical study of SVT treatment with LMWH was organized in 18 outpatient departments in the Slovak Republic. RESULTS: After 10 days of treatment with LMWH in full therapeutic dosage, an improvement in the clinical symptoms was demonstrated in 93 % of patients; a complete resolution of clinical symptoms was demonstrated in 4 % of patients. On day 30 (after 10 days of LMWH treatment in full therapeutic dosage and further treatment in halved therapeutic dosage up to 20 days) a complete resolution of clinical symptoms was observed in 59 % (n = 189) of patients. Patients were further clinically evaluated on day 90, after two months of no anticoagulation treatment. The clinical evaluation revealed a complete resolution of symptoms in 88 % (n = 283) of patients and improvement in symptoms in 11.6 % (n = 34). Two patients developed pulmonary embolization; extension of SVT was seen in one patient and SVT recurrence in two patients. CONCLUSION: Superficial vein thrombosis can propagate into the deep veins with the risk of pulmonary embolism. The results indicate that current ambulatory treatment regimen using LMWH in the treatment of SVT is effective and safe (Fig. 4, Ref. 30). Text in PDF www.elis.sk.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bratislavské lekárske listy

ISSN

0006-9248

e-ISSN

—

Volume of the periodical

117

Issue of the periodical within the volume

10

Country of publishing house

SK - SLOVAKIA

Number of pages

6

Pages from-to

595-600

UT code for WoS article

000387631100008

EID of the result in the Scopus database

2-s2.0-85014962659