Pulmonary dysfunction in patients after cervical spinal cord injury: serial follow-up measurement within the first year post-injury

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332631" target="_blank" >RIV/00064203:_____/16:10332631 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/16:10332631 RIV/00216208:11120/16:43912358

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Pulmonary dysfunction in patients after cervical spinal cord injury: serial follow-up measurement within the first year post-injury

Original language description

OBJECTIVES: Respiratory complications are most common cause of morbidity/ mortality in patients with cervical spinal cord injury (cSCI) due to respiratory muscle weakness and lower diaphragm position resulting in limited availability of inspiration, reduced thorax mobility and limited forced expiration. Differences in respiratory dysfunctions (RDs) in patients with motor complete versus incomplete cSCI were assessed. DESIGN: Prospective longitudinal study, serial measurement. SETTING: University hospital and ambulatory departments. METHODS: Twenty two patients with acute cSCI were recruited. Neurological level of injury and severity according to ISNCSCI were used as criteria for recruitment. Patients were divided into two groups-motor complete and incomplete. Standardized pulmonary function tests (PFT) were used-spirometry and respiratory muscle strength (RMS) measurement. Motor score of key muscles assessments for upper (UEMS) and lower (LEMS) limbs were used. Tests were performed in 5 measurement sessions starting on (medians) 14.5 days (M1), then 6.7 weeks, 3.2 months, 6.3 months and 1.0 year (M5). RESULTS: Significant differences in measurement sessions M2-M5 between groups in forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), expiratory reserve volume (ERV), maximal static inspiratory/expiratory pressures (MIP, MEP) and UEMS were proved. Consequently, prominent differences in courses of particular parameters were found. No intergroup changes in UEMS were found during study. CONCLUSIONS: Obvious differences in parameters of spirometry, respiratory muscles and limb muscles strength between motor complete and incomplete group were found. Carefull monitoring of RDs by functional assessments (i.e., PFT and UEMS/LEMS tests) within one year after SCI seems to be clinically important.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FC - Pneumology

OECD FORD branch

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Project

<a href="/en/project/NT12381" target="_blank" >NT12381: Dysfunction of the respiratory system in patients after spinal cord injury (SCI)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

3

Country of publishing house

SE - SWEDEN

Number of pages

9

Pages from-to

193-201

UT code for WoS article

000388708800008

EID of the result in the Scopus database

2-s2.0-84994226554