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Insulin pump therapy in children with type 1 diabetes: analysis of data from the SWEET registry

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332665" target="_blank" >RIV/00064203:_____/16:10332665 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/16:10332665

  • Result on the web

    <a href="http://dx.doi.org/10.1111/pedi.12416" target="_blank" >http://dx.doi.org/10.1111/pedi.12416</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/pedi.12416" target="_blank" >10.1111/pedi.12416</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Insulin pump therapy in children with type 1 diabetes: analysis of data from the SWEET registry

  • Original language description

    Background: Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes (T1D) to achieve good metabolic control. Objective: To examine the frequency of pump usage in T1D children treated in SWEET (Better control in Paediatric and Adolescent diabeteS: Working to crEate CEnTers of Reference) centers and to compare metabolic control between patients treated with CSII vs MDI. Methods: This study included 16 570 T1D children participating in the SWEET prospective, multicenter, standardized diabetes patient registry. Datasets were aggregated over the most recent year of treatment for each patient. Data were collected until March 2016. To assess the organization of pump therapy a survey was carried out. Results: Overall, 44.4% of T1D children were treated with CSII. The proportion of patients with pump usage varied between centers and decreased with increasing age compared with children treated with MDI. In a logistic regression analysis adjusting for age, gender and diabetes duration, the use of pump was associated with both: center size [odd ratio 1.51 (1.47-1.55), P < .0001) and the diabetes-related expenditure per capita [odd ratio 1.55 (1.49-1.61), P < .0001]. Linear regression analysis, adjusted for age, gender, and diabetes duration showed that both HbA1c and daily insulin dose (U/kg/d) remained decreased in children treated with CSII compared to MDI (P < .0001). Conclusions: Insulin pump therapy is offered by most Sweet centers. The differences between centers affect the frequency of use of modern technology. Despite the heterogeneity of centers, T1D children achieve relatively good metabolic control, especially those treated with insulin pumps and those of younger age.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Pediatric Diabetes

  • ISSN

    1399-543X

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    Supplement 23

  • Country of publishing house

    DK - DENMARK

  • Number of pages

    8

  • Pages from-to

    38-45

  • UT code for WoS article

    000389153800006

  • EID of the result in the Scopus database

    2-s2.0-84992418549