Insulin pump therapy in children with type 1 diabetes: analysis of data from the SWEET registry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332665" target="_blank" >RIV/00064203:_____/16:10332665 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10332665
Result on the web
<a href="http://dx.doi.org/10.1111/pedi.12416" target="_blank" >http://dx.doi.org/10.1111/pedi.12416</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/pedi.12416" target="_blank" >10.1111/pedi.12416</a>
Alternative languages
Result language
angličtina
Original language name
Insulin pump therapy in children with type 1 diabetes: analysis of data from the SWEET registry
Original language description
Background: Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes (T1D) to achieve good metabolic control. Objective: To examine the frequency of pump usage in T1D children treated in SWEET (Better control in Paediatric and Adolescent diabeteS: Working to crEate CEnTers of Reference) centers and to compare metabolic control between patients treated with CSII vs MDI. Methods: This study included 16 570 T1D children participating in the SWEET prospective, multicenter, standardized diabetes patient registry. Datasets were aggregated over the most recent year of treatment for each patient. Data were collected until March 2016. To assess the organization of pump therapy a survey was carried out. Results: Overall, 44.4% of T1D children were treated with CSII. The proportion of patients with pump usage varied between centers and decreased with increasing age compared with children treated with MDI. In a logistic regression analysis adjusting for age, gender and diabetes duration, the use of pump was associated with both: center size [odd ratio 1.51 (1.47-1.55), P < .0001) and the diabetes-related expenditure per capita [odd ratio 1.55 (1.49-1.61), P < .0001]. Linear regression analysis, adjusted for age, gender, and diabetes duration showed that both HbA1c and daily insulin dose (U/kg/d) remained decreased in children treated with CSII compared to MDI (P < .0001). Conclusions: Insulin pump therapy is offered by most Sweet centers. The differences between centers affect the frequency of use of modern technology. Despite the heterogeneity of centers, T1D children achieve relatively good metabolic control, especially those treated with insulin pumps and those of younger age.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric Diabetes
ISSN
1399-543X
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
Supplement 23
Country of publishing house
DK - DENMARK
Number of pages
8
Pages from-to
38-45
UT code for WoS article
000389153800006
EID of the result in the Scopus database
2-s2.0-84992418549