Inter-comparison of quantitative imaging of lutetium-177 (Lu-177) in European hospitals

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F18%3A10377431" target="_blank" >RIV/00064203:_____/18:10377431 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1186/s40658-018-0213-z" target="_blank" >https://doi.org/10.1186/s40658-018-0213-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s40658-018-0213-z" target="_blank" >10.1186/s40658-018-0213-z</a>

Result language

angličtina

Original language name

Inter-comparison of quantitative imaging of lutetium-177 (Lu-177) in European hospitals

Original language description

Background: This inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 (Lu-177) in current clinical practice. Our aim was to assess the feasibility of using international inter-comparison exercises as a means to ensure consistency between clinical sites whilst enabling the sites to use their own choice of quantitative imaging protocols, specific to their systems. Dual-compartment concentric spherical sources of accurately known activity concentrations were prepared and sent to seven European clinical sites. The site staff were not aware of the true volumes or activity within the sources-they performed SPECT/CT imaging of the source, positioned within a water-filled phantom, using their own choice of parameters and reported their estimate of the activities within the source. Results: The volumes reported by the participants for the inner section of the source were all within 29% of the true value and within 60% of the true value for the outer section. The activities reported by the participants for the inner section of the source were all within 20% of the true value, whilst those reported for the outer section were up to 83% different to the true value. Conclusions: A variety of calibration and segmentation methods were used by the participants for this exercise which demonstrated the variability of quantitative imaging across clinical sites. This paper presents a method to assess consistency between sites using different calibration and segmentation methods.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EJNMMI Physics [online]

ISSN

2197-7364

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

neuvedeno

Country of publishing house

CH - SWITZERLAND

Number of pages

18

Pages from-to

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UT code for WoS article

000440432700001

EID of the result in the Scopus database

2-s2.0-85051062090