Optimal Oxygen Saturation in Extremely Premature Neonates

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F19%3A10394207" target="_blank" >RIV/00064203:_____/19:10394207 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/19:10394207
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Xh1HBMi.sd" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Xh1HBMi.sd</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.33549/physiolres.933987" target="_blank" >10.33549/physiolres.933987</a>

Result language
angličtina
Original language name
Optimal Oxygen Saturation in Extremely Premature Neonates
Original language description
So far, great efforts have been made to understand the demands of extremely premature neonates (EPNs'; born before the 28th week of gestation) on postnatal care, including optimal oxygen saturation, that will allow them to survive without disability. A major yet unresolved problem is to find an "optimal range" of their oxygen saturation and to maintain it without drops or increases, i.e., without hypoxia or hyperoxia. The individual sections of this paper deal with the changes of SpO(2) (an estimate of SaO(2) measured by pulse oximetry) that occur before, during, and after premature labor, postnatal factors affecting SpO(2), and especially how to find an acceptable compromise in choosing the most effective and minimally harmful range of SpO(2) for EPNs' with the careful FiO(2) adjustment and continually monitored SpO(2) . At present, the two SpO(2) ranges, narrow (90-94 %) vs. wider (88-94 %), are most discussed. However, the question of how much oxygen is too much or little remains unanswered. There is even a view that there is no uniform optimal SpO(2) range for EPNs, and that each newborn has its own, individually specific range that changes due to its intrinsic and/or extrinsic factors.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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