Mortality in Children Treated With Maintenance Peritoneal Dialysis: Findings From the International Pediatric Peritoneal Dialysis Network Registry

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F21%3A10422595" target="_blank" >RIV/00064203:_____/21:10422595 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/21:10422595

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=zbTVJJUCSY" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=zbTVJJUCSY</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.ajkd.2020.11.031" target="_blank" >10.1053/j.ajkd.2020.11.031</a>

Result language

angličtina

Original language name

Mortality in Children Treated With Maintenance Peritoneal Dialysis: Findings From the International Pediatric Peritoneal Dialysis Network Registry

Original language description

RATIONALE &amp; OBJECTIVE: Research on pediatric kidney replacement therapy (KRT) has primarily focused on Europe and North America. In this study, we aimed to describe the mortality risk of children treated with maintenance peritoneal dialysis (MPD) in different parts of the world and characterize the associated demographic and macro-economic factors. STUDY DESIGN: Prospective cohort study. SETTING &amp; PARTICIPANTS: We evaluated patients aged &lt;19 years at inclusion into the International Pediatric Peritoneal Dialysis Network registry, who initiated MPD between 1996-2017. EXPOSURES: The primary exposure was region (Asia, Western Europe, Eastern Europe, Latin America, North America, and Oceania). Other demographic, clinical and macro-economic (four income groups based on Gross National Income) factors were studied as exposures. OUTCOMES: All-cause MPD mortality. ANALYTICAL APPROACH: Patients were followed for three years. Mortality rates in different regions and income groups were calculated. Cause-specific hazards models with random effects were fit to calculate the proportional change in variance for factors that could explain variation in mortality rates. RESULTS: A total of 2,956 patients with a median age of 7.8 years at the start of KRT were included. After three years, the overall probability of death was 5%, ranging from 2% in North America to 9% in Eastern Europe. Mortality rates were higher in low-income countries than in high-income countries. Income category explained 50.1% of the variance in mortality risk between regions. Other explanatory factors included peritoneal dialysis modality at start (22.5%) and body mass index (11.1%). LIMITATIONS: The interpretation of interregional survival differences as found in this study may be hampered by selection bias. CONCLUSION: This study shows that the overall three-year patient survival on pediatric MPD is high, and that country income is associated with patient survival.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30217 - Urology and nephrology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

American Journal of Kidney Diseases

ISSN

0272-6386

e-ISSN

—

Volume of the periodical

78

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

380-390

UT code for WoS article

000686900900011

EID of the result in the Scopus database

2-s2.0-85105360262