Possible mechanisms of subsequent neoplasia development in childhood cancer survivors: A review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F21%3A10432995" target="_blank" >RIV/00064203:_____/21:10432995 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/21:10432995

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0LFXkmkqkn" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0LFXkmkqkn</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/cancers13205064" target="_blank" >10.3390/cancers13205064</a>

Result language

angličtina

Original language name

Possible mechanisms of subsequent neoplasia development in childhood cancer survivors: A review

Original language description

Advances in medicine have improved outcomes in children diagnosed with cancer, with overall 5-year survival rates for these children now exceeding 80%. Two-thirds of childhood cancer survivors have at least one late effect of cancer therapy, with one-third having serious or even life-threatening effects. One of the most serious late effects is a development of subsequent malignant neoplasms (histologically different cancers, which appear after the treatment for primary cancer), which occur in about 3-10% of survivors and are associated with high mortality. In cancers with a very good prognosis, subsequent malignant neoplasms significantly affect long-term survival. Therefore, there is an effort to reduce particularly hazardous treatments. This review discusses the importance of individual factors (gender, genetic factors, cytostatic drugs, radiotherapy) in the development of subsequent malignant neoplasms and the possibilities of their prediction and prevention in the future.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30205 - Hematology

Project

<a href="/en/project/NV19-03-00245" target="_blank" >NV19-03-00245: Signs of accelerated aging as late effect of therapy for childhood cancer and as risk factor of subsequent malignant neoplasms.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cancers

ISSN

2072-6694

e-ISSN

—

Volume of the periodical

13

Issue of the periodical within the volume

20

Country of publishing house

CH - SWITZERLAND

Number of pages

17

Pages from-to

5064

UT code for WoS article

000715518300001

EID of the result in the Scopus database

2-s2.0-85116828330