A comprehensive validation study of the latest version of BoneXpert on a large cohort of Caucasian children and adolescents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F23%3A10458597" target="_blank" >RIV/00064203:_____/23:10458597 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/23:10458597 RIV/00216208:11310/23:10458597 RIV/00216208:11320/23:10458597
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=evYhK65pVQ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=evYhK65pVQ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fendo.2023.1130580" target="_blank" >10.3389/fendo.2023.1130580</a>
Alternative languages
Result language
angličtina
Original language name
A comprehensive validation study of the latest version of BoneXpert on a large cohort of Caucasian children and adolescents
Original language description
INTRODUCTION: Automated bone age assessment has recently become increasingly popular. The aim of this study was to assess the agreement between automated and manual evaluation of bone age using the method according to Tanner-Whitehouse (TW3) and Greulich-Pyle (GP). METHODS: We evaluated 1285 bone age scans from 1202 children (657 scans from 612 boys) by using both manual and automated (TW3 as well as GP) bone age assessment. BoneXpert software versions 2.4.5.1. (BX2) and 3.2.1. (BX3) (Visiana, Holte, Denmark) were compared with manual evaluation using root mean squared error (RMSE) analysis. RESULTS: RMSE for BX2 was 0.57 and 0.55 years in boys and 0.72 and 0.59 years in girls, respectively for TW3 and GP. For BX3, RMSE was 0.51 and 0.68 years in boys and 0.49 and 0.52 years in girls, respectively for TW3 and GP. Sex- and age-specific analysis for BX2 identified the largest differences between manual and automated TW3 evaluation in girls between 6-7, 12-13, 13-14 and 14-15 years, with RMSE 0.88, 0.81, 0.92 and 0.84 years, respectively. The BX3 version showed better agreement with manual TW3 evaluation (RMSE 0.64, 0.45, 0.46 and 0.57). CONCLUSION: The latest version of the BoneXpert software provides improved and clinically sufficient agreement with manual bone age evaluation in children of both sexes compared to the previous version and may be used for routine bone age evaluation in non-selected cases in pediatric endocrinology care.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30209 - Paediatrics
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Endocrinology
ISSN
1664-2392
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
March
Country of publishing house
CH - SWITZERLAND
Number of pages
9
Pages from-to
1130580
UT code for WoS article
000963418500001
EID of the result in the Scopus database
2-s2.0-85152517601