Cerebral sinovenous thrombosis in children with nephrotic syndrome: systematic review and one new case

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F23%3A10467558" target="_blank" >RIV/00064203:_____/23:10467558 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/23:10467558

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Rmn_v3npKx" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Rmn_v3npKx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fped.2023.1207871" target="_blank" >10.3389/fped.2023.1207871</a>

Result language

angličtina

Original language name

Cerebral sinovenous thrombosis in children with nephrotic syndrome: systematic review and one new case

Original language description

AIM: The aim of this review is to provide clinicians with characteristics of children with nephrotic syndrome and cerebral sinovenous thrombosis (CSVT). METHODS: We have reviewed 37 articles of pediatric cases and provided 1 new case. PRISMA guidelines were followed. RESULTS: Sixty-two patients were included in the review. CSVT was more common in males, usually occurred within 6 months of nephrotic syndrome onset and was found more often in outpatients. The superior sagittal sinus was the most common sinus affected. Non-contrast computed tomography was the most frequent radiologic study performed, with 30% of results negative for CSVT. Headache and vomiting were the most common symptoms while neurologic symptoms were less frequent. Anticoagulation treatment was strongly inconsistent throughout the literature. Thrombosis outcomes were favorable. The most common possible risk factors were corticosteroid treatment, proteinuria and hypoalbuminemia. Four children had a genetic predisposition diagnosed after thrombosis. No markers for anticoagulation prophylaxis seemed to be relevant for the majority of thrombosis occurring in outpatients. CONCLUSION: Prophylactic anticoagulation does not seem reasonable to prevent CSVT. Knowledge of nonspecific symptoms and of nephrotic syndrome being a state of hypercoagulation and early use of appropriate radiologic study seem to be of major importance.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30209 - Paediatrics

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Pediatrics

ISSN

2296-2360

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

August

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

1207871

UT code for WoS article

001059791800001

EID of the result in the Scopus database

2-s2.0-85170542087