Low-Grade Glioma in Children and Adolescents

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F24%3A10497337" target="_blank" >RIV/00064203:_____/24:10497337 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/24:10497337
Result on the web
<a href="https://doi.org/10.1007/978-3-031-62017-1_9" target="_blank" >https://doi.org/10.1007/978-3-031-62017-1_9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-62017-1_9" target="_blank" >10.1007/978-3-031-62017-1_9</a>

Result language
angličtina
Original language name
Low-Grade Glioma in Children and Adolescents
Original language description
Low-grade gliomas are the most common CNS tumours in children and adolescents. Different from their adult counterparts, Paediatric Low-Grade Gliomas (PLGG) have high survival rates with very few patients dying from disease. During the last 15 years, extraordinary biology findings have occurred in these tumours leading to a new WHO 2021 classification based on molecular alterations. A complete pathology-molecular-methylation study is now recommended in these tumours for a precise diagnosis and molecular targets. Surgery is still the main treatment for those resectable tumours. For non-resectable, chemotherapy and radiotherapy (in selected cases) are used. In the last years, targeted therapy is gaining visibility with good results and reasonable toxicity. Long-term quality of life of the patients remains an important aim when choosing the best treatment for these patients.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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