From infancy to toddlerhood: A 3D analysis of facial asymmetry in children with and without orofacial clefts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F25%3A10500075" target="_blank" >RIV/00064203:_____/25:10500075 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/25:43928690 RIV/00216208:11130/25:10500075 RIV/00216208:11150/25:10500075 RIV/00216208:11310/25:10500075
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=61.xTd8l3L" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=61.xTd8l3L</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00784-025-06484-1" target="_blank" >10.1007/s00784-025-06484-1</a>
Alternative languages
Result language
angličtina
Original language name
From infancy to toddlerhood: A 3D analysis of facial asymmetry in children with and without orofacial clefts
Original language description
OBJECTIVES: This study investigates facial directional asymmetry (DA) in early childhood. Using 3D imaging, it aims to assess the DA progression in healthy controls and children with unilateral cleft lip (CL) and unilateral cleft lip and palate (UCLP) following early neonatal cheiloplasty and palatoplasty. MATERIALS & METHODS: The sample consisted of 105 children (groups: cleft 42, control 63) aged 0.2-2 years. DA was analysed using geometric morphometrics, including 3D landmark-based and polygonal mesh analyses. Multivariate statistics were used for assessing DA significance and age group differences. RESULTS: Controls showed no DA in landmarks and only mild protrusion of the right hemiface, increasing with age. In groups with cleft, DA was more pronounced in UCLP and especially in the middle of the face. While older UCLP children showed more asymmetrical faces, DA in children with CL became more comparable to that in controls with increasing age. Older children showed no statistical difference between control and CL in the landmark and polygonal maps parts. CONCLUSIONS: After surgical treatment, a DA pattern was identified, and it was specific for both cleft types and age categories. For both diagnoses, the most notable feature is the protrusion at the cleft site, likely related to post-surgical scarring, but in the UCLP group, it is also the hypoplastic nasal wing and a growth insufficiency of the cheek on the cleft side. CLINICAL RELEVANCE: 3D methodologies provide insight into asymmetry progression and surgical outcomes, supporting improved cleft management for enhanced aesthetic and functional results.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30208 - Dentistry, oral surgery and medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Oral Investigations
ISSN
1432-6981
e-ISSN
1436-3771
Volume of the periodical
29
Issue of the periodical within the volume
8
Country of publishing house
DE - GERMANY
Number of pages
15
Pages from-to
394
UT code for WoS article
001543126300001
EID of the result in the Scopus database
2-s2.0-105012482004