Down-regulated expression of apoptosis-associated genes APIP and UACA in non-amall cell lung carcinoma

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F12%3A%230000128" target="_blank" >RIV/00064211:_____/12:#0000128 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3892/ijo.2012.1397" target="_blank" >http://dx.doi.org/10.3892/ijo.2012.1397</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3892/ijo.2012.1397" target="_blank" >10.3892/ijo.2012.1397</a>

Result language
angličtina
Original language name
Down-regulated expression of apoptosis-associated genes APIP and UACA in non-amall cell lung carcinoma
Original language description
In the present study we investigated the expression status of Apaf-1 interacting protein (APIP) and the uveal autoantigen with coiled coil domains and ankyrin repeats (UACA) in non-small cell lung carcinoma (NSCLC) cells and tumours. We report for the first time that the expression of APIP and UACA genes is down-regulated on the level of both mRNA and protein in NSCLC cells and tumours and discuss the possible impact of these alterations on lung cancer development.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FC - Pneumology
OECD FORD branch
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Project
<a href="/en/project/NS9715" target="_blank" >NS9715: Dysfunction of the apoptosome pathway in non-small cell lung cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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