PREVALENCE OF CHLAMYDIA TRACHOMATIS AND NEISSERIA GONORRHOEAE CO-INFECTIONS AMONG PATIENTS WITH NEWLY DIAGNOSED SYPHILIS: A SINGLE-CENTRE, CROSS-SECTIONAL STUDY

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F19%3AW0002020" target="_blank" >RIV/00064211:_____/19:W0002020 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/19:10403728 RIV/00216208:11120/19:43919627 RIV/00216208:11130/19:10403728 RIV/75010330:_____/19:00012899

Result on the web

<a href="https://oadoi.org/10.21101/cejph.a5142" target="_blank" >https://oadoi.org/10.21101/cejph.a5142</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21101/cejph.a5142" target="_blank" >10.21101/cejph.a5142</a>

Result language

angličtina

Original language name

PREVALENCE OF CHLAMYDIA TRACHOMATIS AND NEISSERIA GONORRHOEAE CO-INFECTIONS AMONG PATIENTS WITH NEWLY DIAGNOSED SYPHILIS: A SINGLE-CENTRE, CROSS-SECTIONAL STUDY

Original language description

Objectives: The aim of the study was to determine the prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae co-infections among patients with newly diagnosed syphilis. Methods: In patients with any stage of newly diagnosed syphilis swabs were performed from urethra, rectum, pharynx and cervix according to the gender and type of sexual intercourse. From these smears standard validated nucleic acid amplification tests (NAATs) for Chlamydia trachomatis and Neisseria gonorrhoeae infections were done. Results: From 548 (488 men, 60 women) screened patients co-infection was detected in 15.9% of the cases. The majority of the co-infections (86.2%) were asymptomatic. The overall prevalence of chlamydial infection was 11.1% and 8.8% for gonococcal infections. In men who have sex with men (MSM) the prevalence of co-infections was significantly higher (20.0%) than in heterosexual men and women (4.2%) (p <0.001). In MSM patients the presence of co-infection was significantly associated with HIV infection (p <0.001). Among MSM 9.6% of the tests detected infection in anorectal site, while prevalence in urethral (2.8%) and pharyngeal (2.4%) localization was significantly lower. In heterosexual patients prevalence was less than 2.0% in all anatomic sites. Conclusions: The implementation of screening tests in case of sexually transmitted infections in patients with newly diagnosed syphilis is an important part in the management of this disease. These results suggest that screening of asymptomatic heterosexual patients leads to detection of minimum co-infections, but in MSM (especially HIV positive) should always be performed at least in anorectal site, where asymptomatic co-infections are common.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30304 - Public and environmental health

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH

ISSN

1210-7778

e-ISSN

1803-1048

Volume of the periodical

27

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

285-291

UT code for WoS article

000514475600004

EID of the result in the Scopus database

2-s2.0-85078016118