Impact of comorbidity scores and lifestyle factors in curative radiotherapy in laryngeal cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F23%3AW0000024" target="_blank" >RIV/00064211:_____/23:W0000024 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10465275 RIV/00064190:_____/23:10001153
Result on the web
<a href="https://oadoi.org/10.1007/s00066-023-02072-y" target="_blank" >https://oadoi.org/10.1007/s00066-023-02072-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00066-023-02072-y" target="_blank" >10.1007/s00066-023-02072-y</a>
Alternative languages
Result language
angličtina
Original language name
Impact of comorbidity scores and lifestyle factors in curative radiotherapy in laryngeal cancer
Original language description
PurposeThe principal goal of treatment of laryngeal cancer is to eliminate a tumour while preserving laryngeal function with radio(chemo)therapy being the mainstay of treatment. The aim of this report is to present the influence of comorbidities and lifestyle factors on treatment outcomes in our cohort of patients.MethodsDuring the period 2009-2018, curative radio(chemo)therapy for laryngeal cancer was performed on 189 patients.ResultsThe median OS was 50.8 months, with a mean PFS of 96.5 months, mean LC of 101.4 months and a median follow-up of 38.1 months. Acute and late treatment toxicity grade 3-4 was observed in 39.2% patients and 10.1% patients, respectively. A significant effect on overall survival was confirmed for the baseline PS (performance status), severity of weight loss, baseline haemoglobin values, history of alcohol abuse, marital status and comorbidities according to the Charlson Comorbidity Index, as well as the ACE-27 and ASA scores.ConclusionsIn our cohort of patients treated with radio(chemo)therapy for laryngeal cancer, we found good therapeutic results and an acceptable side-effect profile. Statistically significant predictors of overall survival were the baseline PS, weight loss, anaemia, associated comorbidities, history of alcohol abuse and marital status.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30204 - Oncology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
STRAHLENTHERAPIE UND ONKOLOGIE
ISSN
0179-7158
e-ISSN
1439-099X
Volume of the periodical
199
Issue of the periodical within the volume
10
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
881-890
UT code for WoS article
000970942400002
EID of the result in the Scopus database
2-s2.0-85152422043