Vulvodynia and Muscle Hypoxia: A Critical Correlation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F25%3AW0000009" target="_blank" >RIV/00064211:_____/25:W0000009 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10497340 RIV/00216208:11510/25:10497340

Result on the web

<a href="https://www.actualgyn.com/pdf/en_2025_306.pdf" target="_blank" >https://www.actualgyn.com/pdf/en_2025_306.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Vulvodynia and Muscle Hypoxia: A Critical Correlation

Original language description

Introduction: Idiopathic vulvodynia is a chronic pain syndrome affecting the vulvar area. It severely affects quality of life. Chronic perineal muscle hypoxia may contribute to persistent pain that is refractory to conventional treatments. In our previous study on acute pain syndrome dyspareunia, we found significantly low pulse oximetry levels in the perigenital area of afflicted women. Aims: Our intention was to compare pulse oximetry saturation (SpO(2)) in women affected by vulvodynia with healthy individuals. Design: A retrospective study design was adopted. Participants: The study included 62 participants, with 31 women in the treatment group and 31 in the control group. The participants were women who participated in our previous study on vulvodynia. Methods: Participants were measured for SpO(2) during their regular examinations. The measurement was performed in the perigenital area, specifically the posterior commissure and the spongiosus muscle. Results: The median SpO(2) was 90% in the treatment group and 92% in the controls. This difference was statistically significant (p < .001). The sample size was statistically adequate. Discussion: We observed clinically significant decreased levels of SpO(2) in women with idiopathic chronic vulvodynia compared to healthy controls. This comparison highlighted significant hypoxia in the perigenital muscles and the perimuscular area (p < .001). These findings enhance our understanding of chronic vulvodynia and may inform treatment strategies.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

AKTUALNI GYNEKOLOGIE A PORODNICTVI

ISSN

1803-9588

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

2025

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

37-40

UT code for WoS article

001462527900001

EID of the result in the Scopus database

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