Treatment with statins and involvement of the peripheral nervous system: results of a prospective clinical and neurophysiological follow-up.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F07%3A%230000102" target="_blank" >RIV/00098892:_____/07:#0000102 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/07:#0000204

Result on the web

<a href="http://biomed.papers.upol.cz" target="_blank" >http://biomed.papers.upol.cz</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Treatment with statins and involvement of the peripheral nervous system: results of a prospective clinical and neurophysiological follow-up.

Original language description

AIMS: To study the pathological changes in neurophysiological examination of lower-limb peripheral nerves in patients with long-term statin treatment. METHODS: Forty-two patients (23 males, 19 females, mean age 51.9 and 52.3 years) with a definitive diagnosis of combined hyperlipidemia were studied. Other metabolic disorders or chronic ethanol abuse were excluded. Initial examinations included laboratory and neurophysiological measures (peroneal and tibial nerves: MNCV, CMAP, F-wave mean latency; superficial peroneal and sural nerve: SNCV, SNAP). Subsequently, treatment with simvastatin 20mg daily was initiated. Patients were followed for 24 months with examinations at 1, 6, 12 and 24 months after statin treatment initiation. RESULTS: None of the patients reported subjective symptoms typical for polyneuropathy. In laboratory findings, there was no elevation of muscle enzymes. Nevertheless, electrophysiological examination of lower-limb peripheral nerves demonstrated statistically signi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical papers

ISSN

1213-8118

e-ISSN

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Volume of the periodical

151

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

307-310

UT code for WoS article

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EID of the result in the Scopus database

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