Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F16%3AN0000144" target="_blank" >RIV/00098892:_____/16:N0000144 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/16:33160342

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S2049080116300401" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2049080116300401</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.amsu.2016.04.022" target="_blank" >10.1016/j.amsu.2016.04.022</a>

Result language

angličtina

Original language name

Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review

Original language description

Introduction:Acute pancreatitis is a rare but frequently fatal complication in patients following kidneytransplantation. Thefirst case of acute pancreatitis in patients following a kidney transplant wasdescribed by Starzl in 1964. The incidence of acute pancreatitis is stated at between 1 and 5%. Themortality rate amongst these patients reaches as high as 50e100%.Presentation of case:Here we present a case of acute pancreatic abscess in a caucasian femaleeshortlyfollowing a kidney transplant complicated by the development of acute rejection, in which immuno-suppressant therapy is a potential etiological agent. Emergency surgical treatment was indicated, whichincluded drainage of the abscesses irrigation of the abdominal cavity. Immunosuppressive medicationwas considered a possible etiological factor, and as a result administration of tacrolimus and myco-phenolate mofetil was discontinued. This was successful and three months later, diagnostic rebiopsy ofthe graft was performed without signs of rejection.Discussion:The etiology of this illness is multifactorial. The clinical manifestation of acute pancreatitis inpatients following kidney transplantation is the same as in the remainder of the population. However, inpatients following transplantation with long-term immunosuppression, it usually manifests a more rapiddevelopment and a more severe, frequently fatal course.Conclusions:With regard to the patient's comorbidities, early surgical therapy was indicatededrainageand closed lavage and immunosuppressive medication as a suspected tobe ethiological factor was dis-continued. This course of treatment led to a complete recovery with preservation of good function of thecadaverous kidney.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30218 - General and internal medicine

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Medicine and Surgery  

ISSN

2049-0801

e-ISSN

2049-0801

Volume of the periodical

8

Issue of the periodical within the volume

June

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

14-17

UT code for WoS article

000377037300003

EID of the result in the Scopus database

2-s2.0-84965067420