Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F16%3AN0000144" target="_blank" >RIV/00098892:_____/16:N0000144 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/16:33160342
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2049080116300401" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2049080116300401</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.amsu.2016.04.022" target="_blank" >10.1016/j.amsu.2016.04.022</a>
Alternative languages
Result language
angličtina
Original language name
Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review
Original language description
Introduction:Acute pancreatitis is a rare but frequently fatal complication in patients following kidneytransplantation. Thefirst case of acute pancreatitis in patients following a kidney transplant wasdescribed by Starzl in 1964. The incidence of acute pancreatitis is stated at between 1 and 5%. Themortality rate amongst these patients reaches as high as 50e100%.Presentation of case:Here we present a case of acute pancreatic abscess in a caucasian femaleeshortlyfollowing a kidney transplant complicated by the development of acute rejection, in which immuno-suppressant therapy is a potential etiological agent. Emergency surgical treatment was indicated, whichincluded drainage of the abscesses irrigation of the abdominal cavity. Immunosuppressive medicationwas considered a possible etiological factor, and as a result administration of tacrolimus and myco-phenolate mofetil was discontinued. This was successful and three months later, diagnostic rebiopsy ofthe graft was performed without signs of rejection.Discussion:The etiology of this illness is multifactorial. The clinical manifestation of acute pancreatitis inpatients following kidney transplantation is the same as in the remainder of the population. However, inpatients following transplantation with long-term immunosuppression, it usually manifests a more rapiddevelopment and a more severe, frequently fatal course.Conclusions:With regard to the patient's comorbidities, early surgical therapy was indicatededrainageand closed lavage and immunosuppressive medication as a suspected tobe ethiological factor was dis-continued. This course of treatment led to a complete recovery with preservation of good function of thecadaverous kidney.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30218 - General and internal medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Medicine and Surgery
ISSN
2049-0801
e-ISSN
2049-0801
Volume of the periodical
8
Issue of the periodical within the volume
June
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
14-17
UT code for WoS article
000377037300003
EID of the result in the Scopus database
2-s2.0-84965067420