Systemic biomarkers of allogeneic haematopoietic stem cell transplantation outcome-Brief introduction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F19%3AN0000191" target="_blank" >RIV/00098892:_____/19:N0000191 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1111/tan.13761" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/tan.13761</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/tan.13761" target="_blank" >10.1111/tan.13761</a>
Alternative languages
Result language
angličtina
Original language name
Systemic biomarkers of allogeneic haematopoietic stem cell transplantation outcome-Brief introduction
Original language description
Although complex approaches in haematopoietic stem cell transplantation (aHSCT) improved substantially in the last decades, considerable proportion of patients still suffer from life-threatening complications including graft versus host disease (GvHD). Great effort has therefore been dedicated to identification of biomarkers of the aHSCT outcome. Recently, prognostic scores for the prediction of GvHD and non-relapse mortality based on circulating molecules, such as tumour necrosis factor receptor-1, IL-33receptor (ST2) and regenerating islet-derived 3-alpha were proposed and evaluated in multicentre studies. Furthermore, several biomarkers, for example, ST2, represent promising targets for therapeutic intervention in severe GvHD. These results bring us closer to the clinical strategies to effectively control complications following aHSCT, and therefore to the tailored stem cell therapy with higher benefits for the patients.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
HLA
ISSN
2059-2302
e-ISSN
2059-2310
Volume of the periodical
94
Issue of the periodical within the volume
Suppl. S2
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
25-29
UT code for WoS article
000521282900006
EID of the result in the Scopus database
2-s2.0-85076887994