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Systemic biomarkers of allogeneic haematopoietic stem cell transplantation outcome-Brief introduction

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F19%3AN0000191" target="_blank" >RIV/00098892:_____/19:N0000191 - isvavai.cz</a>

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1111/tan.13761" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/tan.13761</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/tan.13761" target="_blank" >10.1111/tan.13761</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Systemic biomarkers of allogeneic haematopoietic stem cell transplantation outcome-Brief introduction

  • Original language description

    Although complex approaches in haematopoietic stem cell transplantation (aHSCT) improved substantially in the last decades, considerable proportion of patients still suffer from life-threatening complications including graft versus host disease (GvHD). Great effort has therefore been dedicated to identification of biomarkers of the aHSCT outcome. Recently, prognostic scores for the prediction of GvHD and non-relapse mortality based on circulating molecules, such as tumour necrosis factor receptor-1, IL-33receptor (ST2) and regenerating islet-derived 3-alpha were proposed and evaluated in multicentre studies. Furthermore, several biomarkers, for example, ST2, represent promising targets for therapeutic intervention in severe GvHD. These results bring us closer to the clinical strategies to effectively control complications following aHSCT, and therefore to the tailored stem cell therapy with higher benefits for the patients.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30102 - Immunology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    HLA

  • ISSN

    2059-2302

  • e-ISSN

    2059-2310

  • Volume of the periodical

    94

  • Issue of the periodical within the volume

    Suppl. S2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    25-29

  • UT code for WoS article

    000521282900006

  • EID of the result in the Scopus database

    2-s2.0-85076887994