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Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F21%3A10157119" target="_blank" >RIV/00098892:_____/21:10157119 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/21:43921820 RIV/00064173:_____/21:N0000076

  • Result on the web

    <a href="https://www.ahajournals.org/doi/10.1161/JAHA.119.014059" target="_blank" >https://www.ahajournals.org/doi/10.1161/JAHA.119.014059</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1161/JAHA.119.014059" target="_blank" >10.1161/JAHA.119.014059</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

  • Original language description

    Background: Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results: Patients with TTS were enrolled from the International Takotsubo Registry, which is a multinational network with 26 participating centers in Europe and the United States. Patients were dichotomized according to the presence or absence of AF at the time of admission. Of 1584 patients with TTS, 112 (7.1%) had AF. The mean age was higher (P&lt;0.001), and there were fewer women (P=0.046) in the AF than in the non-AF group. Left ventricular ejection fraction was significantly lower (P=0.001), and cardiogenic shock was more often observed (P&lt;0.001) in the AF group. Both in-hospital (P&lt;0.001) and long-term mortality (P&lt;0.001) were higher in the AF group. Multivariable Cox regression analysis revealed that AF was independently associated with higher long-term mortality (hazard ratio, 2.31; 95% CI, 1.50-3.55; P&lt;0.001). Among patients with AF on admission, 42% had no known history of AF before the acute TTS event, and such patients had comparable in-hospital and long-term outcomes compared with those with a history of AF. Conclusions: In patients presenting with TTS, AF on admission is significantly associated with increased in-hospital and long-term mortality rates. Whether antiarrhythmics and/or cardioversion are beneficial in TTS with AF should thus be tested in a future trial.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of the American Heart Association

  • ISSN

    2047-9980

  • e-ISSN

    2047-9980

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    15

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    "e014059"

  • UT code for WoS article

    000680426800023

  • EID of the result in the Scopus database

    2-s2.0-85112114406