Development and performance assessment of an advanced Lucas-Kanade algorithm for dose mapping of cervical cancer external radiotherapy and brachytherapy plans
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F21%3AN0000126" target="_blank" >RIV/00098892:_____/21:N0000126 - isvavai.cz</a>
Result on the web
<a href="https://aapm.onlinelibrary.wiley.com/doi/10.1002/acm2.13249" target="_blank" >https://aapm.onlinelibrary.wiley.com/doi/10.1002/acm2.13249</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/acm2.13249" target="_blank" >10.1002/acm2.13249</a>
Alternative languages
Result language
angličtina
Original language name
Development and performance assessment of an advanced Lucas-Kanade algorithm for dose mapping of cervical cancer external radiotherapy and brachytherapy plans
Original language description
Purpose: The aim of this study was to verify the possibility of summing the dose distributions of combined radiotherapeutic treatment of cervical cancer using the extended Lucas-Kanade algorithm for deformable image registration. Materials and methods: First, a deformable registration of planning computed tomography images for the external radiotherapy and brachytherapy treatment of 10 patients with different parameter settings of the Lucas-Kanade algorithm was performed. By evaluating the registered data using landmarks distance, root mean square error of Hounsfield units and 2D gamma analysis, the optimal parameter values were found. Next, with another group of 10 patients, the accuracy of the dose mapping of the optimized Lucas-Kanade algorithm was assessed and compared with Horn-Schunck and modified Demons algorithms using dose differences at landmarks. Results: The best results of the Lucas-Kanade deformable registration were achieved for two pyramid levels in combination with a window size of 3 voxels. With this registration setting, the average landmarks distance was 2.35 mm, the RMSE was the smallest and the average gamma score reached a value of 86.7%. The mean dose difference at the landmarks after mapping the external radiotherapy and brachytherapy dose distributions was 1.33 Gy. A statistically significant difference was observed on comparing the Lucas-Kanade method with the Horn-Schunck and Demons algorithms, where after the deformable registration, the average difference in dose was 1.60 Gy (P-value: 0.0055) and 1.69 Gy (P-value: 0.0012), respectively. Conclusion: Lucas-Kanade deformable registration can lead to a more accurate model of dose accumulation and provide a more realistic idea of the dose distribution.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Applied Clinical Medical Physics
ISSN
1526-9914
e-ISSN
1526-9914
Volume of the periodical
22
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
69-78
UT code for WoS article
000646677500001
EID of the result in the Scopus database
2-s2.0-85105643407