Ocular hypertension in patients with active thyroid-associated orbitopathy: a predictor of disease severity, particularly of extraocular muscle enlargement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F22%3A10157560" target="_blank" >RIV/00098892:_____/22:10157560 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/22:73615729
Result on the web
<a href="https://link.springer.com/article/10.1007/s00417-022-05760-0" target="_blank" >https://link.springer.com/article/10.1007/s00417-022-05760-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00417-022-05760-0" target="_blank" >10.1007/s00417-022-05760-0</a>
Alternative languages
Result language
angličtina
Original language name
Ocular hypertension in patients with active thyroid-associated orbitopathy: a predictor of disease severity, particularly of extraocular muscle enlargement
Original language description
The purpose was to ascertain if any relation exists between the elevated intraocular pressure (IOP) in patients with thyroid-associated orbitopathy (TAO) in active stage and the severity of extraocular muscle involvement and the extent of exophthalmos. Methods: A total of 96 eyes and orbits of 48 adult patients with active TAO were investigated. All patients underwent magnetic resonance imaging of the orbit and measurement of all extraocular recti muscles (EOM). The obtained data was divided into two groups according to the IOP value: normal IOP ≤ 21 mmHg; n=47 and elevated IOP with IOP > 21 mmHg; n=49, and analyszed. Results: A signifcant diference was found in the short diameter of medial rectus and inferior rectus muscles and in the sum of short parameters of all EOM. All these parameters were signifcantly higher in the elevated IOP group. Motility restriction in at least one gaze direction was also signifcantly more frequent (p < 0.0001) in the elevated IOP group. A positive moderate correlation was found between IOP and the sum of short parameters of EOM (r=0.496). No correlation was found between the IOP and exophthalmos values (r=0.267). During the follow-up, the frequency of strabismus surgery and orbital decompression was signifcantly higher in the elevated IOP group (p=0.003; p=0.002). Conclusion: Elevated IOP in the active TAO stage particularly correlates with extraocular muscle involvement. These patients are also more likely to require orbital decompression and strabismus surgery.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30207 - Ophthalmology
Result continuities
Project
<a href="/en/project/NU21J-01-00017" target="_blank" >NU21J-01-00017: Early detection of Graves’ Orbitopathy development in patients with thyroid dysfunction and methods for assessing its activity and severity</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Graefe's archive for clinical and experimental ophthalmology.
ISSN
0721-832X
e-ISSN
1435-702X
Volume of the periodical
260
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
3977-3984
UT code for WoS article
000825175900001
EID of the result in the Scopus database
2-s2.0-85134317857