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Comparing Digital Therapeutic Intervention with an Intensive Obesity Management Program: Randomized Controlled Trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F22%3A10157822" target="_blank" >RIV/00098892:_____/22:10157822 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/22:10445021 RIV/00216224:14110/22:00125801

  • Result on the web

    <a href="https://www.mdpi.com/2072-6643/14/10/2005" target="_blank" >https://www.mdpi.com/2072-6643/14/10/2005</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/nu14102005" target="_blank" >10.3390/nu14102005</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comparing Digital Therapeutic Intervention with an Intensive Obesity Management Program: Randomized Controlled Trial

  • Original language description

    In this study, we evaluated whether the digital program Vitadio achieves comparable results to those of an intensive in-person lifestyle intervention in obesity management. This is a 12-month prospective, randomized controlled trial. Obese patients with insulin resistance, prediabetes or type 2 diabetes were included. The intervention group (IG) used Vitadio. The control group (CG) received a series of in-person consultations. Body weight and various metabolic parameters were observed and analyzed with ANOVA. The trial is ongoing and the presented findings are preliminary. Among 100 participants (29% men; mean age, 43 years; mean BMI, 40.1 kg/m2), 78 completed 3-month follow-up, and 51 have completed the 6-month follow-up so far. Participants significantly (p < 0.01) reduced body weight at 3 months (IG: -5.9 ± 5.0%; CG: -4.2 ± 5.0%) and 6 months (IG: -6.6 ± 6.1%; CG: -7.1 ± 7.1%), and the difference between groups was not significant. The IG achieved favorable change in body composition; significant improvement in TAG (-0.6 ± 0.9 mmol/l, p < 0.01), HDL (0.1 ± 0.1%, p < 0.05), HbA1c (-0.2 ± 0.5%, p < 0.05) and FG (-0.5 ± 1.5 mmol/l, p < 0.05); and a superior (p = 0.02) HOMA-IR reduction (-2.5 ± 5.2, p < 0.01). The digital intervention achieved comparable results to those of the intensive obesity management program. The results suggest that Vitadio is an effective tool for supporting patients in obesity management and diabetes prevention.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30306 - Sport and fitness sciences

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nutrients

  • ISSN

    2072-6643

  • e-ISSN

    2072-6643

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    14

  • Pages from-to

    2005

  • UT code for WoS article

    000801761100001

  • EID of the result in the Scopus database

    2-s2.0-85131108459