Expansive intracardiac leiomyosarcoma – a combined therapeutic approach resulting in survival with complete remission. A literature review and case report
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F23%3A10157469" target="_blank" >RIV/00098892:_____/23:10157469 - isvavai.cz</a>
Result on the web
<a href="https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3131&back=%2Fsearch.php%3Fquery%3DJan%2BJuchelka%2Bin%253Aauth%2Bname%2Bkey%2Babstr%26sfrom%3D0%26spage%3D30" target="_blank" >https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3131&back=%2Fsearch.php%3Fquery%3DJan%2BJuchelka%2Bin%253Aauth%2Bname%2Bkey%2Babstr%26sfrom%3D0%26spage%3D30</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2022.011" target="_blank" >10.5507/bp.2022.011</a>
Alternative languages
Result language
angličtina
Original language name
Expansive intracardiac leiomyosarcoma – a combined therapeutic approach resulting in survival with complete remission. A literature review and case report
Original language description
Primary cardiac sarcomas are extremely rare and often with dismal prognosis. Only a few case series and retrospective studies regarding its biological characteristics, diagnostics, and treatment were reported. The multi-modality therapeutic strategy has been discussed in the published literature, but often with contradictory results. There is thus, no consensus on the optimal therapeutic approach to date. We present the case report of the 66-year old female endangered by a large primary leiomyosarcoma expanding in the right-sided heart chambers with imminent risk of acute obstruction of blood flow. The patient was managed by urgent surgical resection. After the histological confirmation of incomplete R1 resection, the treatment was supplemented by adjuvant CT-targeted radiotherapy, resulting in extraordinary survival with complete remission over a 24-month follow-up period. Our case report aims to demonstrate a favorable result of an individually suited complex surgical and oncological treatment to support the multidisciplinary therapeutic approach to these patients. The article is supplemented by a detailed literature review providing a theoretical background and an overview of the acquired knowledge and possible strategies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers
ISSN
1213-8118
e-ISSN
1804-7521
Volume of the periodical
167
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
116-120
UT code for WoS article
000772174100001
EID of the result in the Scopus database
2-s2.0-85162851826