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Floppy iris syndrome associated with specific medication intake: A narrative review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F23%3A10157572" target="_blank" >RIV/00098892:_____/23:10157572 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/23:73616823

  • Result on the web

    <a href="https://biomed.papers.upol.cz/artkey/bio-202301-0002_floppy-iris-syndrome-associated-with-specific-medication-intake-a-narrative-review.php" target="_blank" >https://biomed.papers.upol.cz/artkey/bio-202301-0002_floppy-iris-syndrome-associated-with-specific-medication-intake-a-narrative-review.php</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2022.042" target="_blank" >10.5507/bp.2022.042</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Floppy iris syndrome associated with specific medication intake: A narrative review

  • Original language description

    Intraoperative floppy iris syndrome (IFIS) is a cataract surgery complication that remains a challenge for eye surgeons. It is caused by the antagonism of alfa-1-adrenergic receptors within the dilator muscle of the iris, thus preventing the iris from dilation during a cataract surgery. The long-term blocking alfa-1 adrenergic receptors by the chronic use of a number of systemic medications may lead to permanent anatomical atrophy of the dilator muscle of the iris. The most common drugs associated with the development of IFIS are tamsulosin and other alpha-1 adrenergic receptor antagonists prescribed to patients with low urinary tract symptoms (LUTS). There are other systemic medications that have been reported to have increased risk for IFIS. It is crucial for the ophthalmologist to identify the high-risk patients prone to develop IFIS. Its presence may complicate the course of cataract surgery, ultimately negatively affecting visual outcome. Cataract surgery should be performed by an experienced eye surgeon using alternative pharmacological and surgical techniques. Interdisciplinary cooperation is essential to mitigate potential complications. Patients should be informed by their physicians about the need to report a medication history to their eye specialists, especially before cataract surgery.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30207 - Ophthalmology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers

  • ISSN

    1213-8118

  • e-ISSN

    1804-7521

  • Volume of the periodical

    167

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    9-15

  • UT code for WoS article

    000870057500001

  • EID of the result in the Scopus database

    2-s2.0-85150312766