Ethanol ablation of thyroid cysts in the young with a focus on efficacy and quality of life
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F23%3A10158161" target="_blank" >RIV/00098892:_____/23:10158161 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/23:73619811 RIV/61989592:15210/23:73619811
Result on the web
<a href="https://etj.bioscientifica.com/view/journals/etj/12/5/ETJ-23-0085.xml" target="_blank" >https://etj.bioscientifica.com/view/journals/etj/12/5/ETJ-23-0085.xml</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1530/ETJ-23-0085" target="_blank" >10.1530/ETJ-23-0085</a>
Alternative languages
Result language
angličtina
Original language name
Ethanol ablation of thyroid cysts in the young with a focus on efficacy and quality of life
Original language description
Objective: Ultrasound-guided percutaneous ethanol injection therapy (US-PEIT) is used in patients with recurrent symptomatic thyroid cysts as a credible alternative to surgery. Young patients commonly do not wish to undergo surgery and prefer ethanol ablation, if available. The effect of this approach on quality of life is an essential factor in deciding on the treatment options, especially in the young with a long life expectancy and no comorbidity. Methods: We performed US-PEIT in a cohort of young patients, 15–30 years, from 2015 to 2020. The patients' general quality of life (QoL), self-reported compression symptoms and neck appearance were evaluated. Results: The cohort comprised 59 patients with 63 cysts, more women than men, with a mean age of 23.8 years. About 1.5 mL of injected alcohol were needed to reach a 90.7% mean cyst volume reduction ratio in 12 months. The method did not fail in any of the patients; a single US-PEIT session was undertaken in 46% of them. The procedure significantly improved each of the patients' symptoms with a significant total score difference (P < 0.001). The total symptom score correlated with the initial cyst volume (P = 0.002; r = 0.395). The mean QoL score by SF-36 6 months after the last US-PEIT was significantly different for physical component summary 56.5 (P < 0.001) but not different for mental component summary 47.7 (P = 0.125), compared to age-corresponding norms. Conclusions: US-PEIT is a safe and effective method for the young, leading to improvements in cosmetic and subjective complaints, and should also be considered as first-line treatment in the young.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Thyroid Journal
ISSN
2235-0640
e-ISSN
2235-0802
Volume of the periodical
12
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
"e230085"
UT code for WoS article
001082879100006
EID of the result in the Scopus database
2-s2.0-85172388679