Primary Squamous Cell Carcinoma of the Parotid Gland: Study and Review of the Literature
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F24%3A10158602" target="_blank" >RIV/00098892:_____/24:10158602 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/24:10473083 RIV/61989592:15110/24:73621307 RIV/00064203:_____/24:10473083
Result on the web
<a href="https://iv.iiarjournals.org/content/38/1/358" target="_blank" >https://iv.iiarjournals.org/content/38/1/358</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21873/invivo.13446" target="_blank" >10.21873/invivo.13446</a>
Alternative languages
Result language
angličtina
Original language name
Primary Squamous Cell Carcinoma of the Parotid Gland: Study and Review of the Literature
Original language description
Background/Aim: Primary squamous cell carcinoma of the parotid gland (pPSCC) is a rare tumor, accounting for less than 3% of all parotid carcinomas. There is no general consensus on the management of this tumor, since clinical experience for pPSCC is minimal. Moreover, pPSCC is often misdiagnosed for metastatic cutaneous carcinoma. In our study, we focused on evaluating its biological and clinical characteristics, treatment results and prognosis. We proposed an update on diagnostic and therapeutic management of pPSCC. Patients and Methods: The retrospective cohort included 18 patients diagnosed and treated for pPSCC in three tertiary head and neck centers between 2008 and 2022. We retrospectively evaluated their prognosis and established a therapeutic recommendation after analyzing our own and previously published data. Results: Fourteen of 18 tumors were diagnosed in stage IV. Five-year overall survival was 36 months. Six patients received palliative therapy. Twelve patients underwent parotidectomy, neck dissection, and adjuvant radiotherapy. Remission was achieved in 8 patients (follow-up interval 3-56 months). One patient died with recurrent disease. The others are alive and in complete remission. Conclusion: The definitive diagnosis of pPSCC must meet the histological and clinical criteria. First of all, the metastatic origin of the tumor must be excluded. Five-year survival of this very aggressive tumor does not exceed 50%. Without surgery, the prognosis is poor. The best results, irrespective of tumor stage, are achieved with surgery. Therefore, a total parotidectomy, neck dissection (therapeutic or elective) and adjuvant radiotherapy are indicated for all resectable tumors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30206 - Otorhinolaryngology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
In Vivo
ISSN
0258-851X
e-ISSN
1791-7549
Volume of the periodical
38
Issue of the periodical within the volume
1
Country of publishing house
GR - GREECE
Number of pages
7
Pages from-to
358-364
UT code for WoS article
001135137400023
EID of the result in the Scopus database
2-s2.0-85180825383