Direct mailing of HPV self-sampling kits to women aged 50–65 non-participating in cervical screening in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F24%3A10158620" target="_blank" >RIV/00098892:_____/24:10158620 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00135936 RIV/00216208:11110/24:10478392 RIV/61989592:15110/24:73625104 RIV/00064165:_____/24:10478392

Result on the web

<a href="https://academic.oup.com/eurpub/article/34/2/361/7542404?login=false" target="_blank" >https://academic.oup.com/eurpub/article/34/2/361/7542404?login=false</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/eurpub/ckad229" target="_blank" >10.1093/eurpub/ckad229</a>

Result language

angličtina

Original language name

Direct mailing of HPV self-sampling kits to women aged 50–65 non-participating in cervical screening in the Czech Republic

Original language description

Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50–65 non-participating in screening. Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model. Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2–15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6–6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0–10.2%; P &lt; 0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination. Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30304 - Public and environmental health

Project

<a href="/en/project/EF16_013%2F0001818" target="_blank" >EF16_013/0001818: Modernization and support of research activities of the national infrastructure for translational medicine EATRIS-CZ</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Public Health

ISSN

1101-1262

e-ISSN

1464-360X

Volume of the periodical

34

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

361-367

UT code for WoS article

001147898300001

EID of the result in the Scopus database

2-s2.0-85189660731