Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F24%3A10158649" target="_blank" >RIV/00098892:_____/24:10158649 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/24:73625001 RIV/60461373:22330/24:43930259

Result on the web

<a href="https://pubs.acs.org/doi/10.1021/acs.jnatprod.3c00961" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.jnatprod.3c00961</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.jnatprod.3c00961" target="_blank" >10.1021/acs.jnatprod.3c00961</a>

Result language

angličtina

Original language name

Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties

Original language description

Advancements in small-molecule research have created the need for sensitive techniques to accurately study biological processes in living systems. Fluorescent-labeled probes have become indispensable tools, particularly those that use boron–dipyrromethene (BODIPY) dyes. Terpenes and terpenoids are organic compounds found in nature that offer diverse biological activities, and BODIPY-based probes play a crucial role in studying these compounds. Monoterpene–BODIPY conjugates have exhibited potential for staining bacterial and fungal cells. Sesquiterpene–BODIPY derivatives have been used to study sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA), indicating their potential for drug development. Owing to their unique properties, diterpenes have been investigated using BODIPY conjugates to evaluate their mechanisms of action. Triterpene–BODIPY conjugates have been synthesized for biological studies, with different spacers affecting their cytotoxicity. Fluorescent probes, inspired by terpenoid-containing vitamins, have also been developed. Derivatives of tocopherol, coenzyme Q10, and vitamin K1 can provide insights into their oxidation–reduction abilities. All these probes have diverse applications, including the study of cell membranes to investigate immune responses and antioxidant properties. Further research in this field can help better understand and use terpenes and terpenoids in various biological contexts.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30107 - Medicinal chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Natural Products

ISSN

0163-3864

e-ISSN

1520-6025

Volume of the periodical

87

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

14

Pages from-to

1306-1319

UT code for WoS article

001185406700001

EID of the result in the Scopus database

2-s2.0-85187695747