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Characterization of cervical fluid Ureaplasma species in pregnant women with spontaneous preterm delivery

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F25%3A10159421" target="_blank" >RIV/00098892:_____/25:10159421 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/25:10502994 RIV/00216208:11150/25:10502994

  • Result on the web

    <a href="https://www.nature.com/articles/s41598-025-16612-2" target="_blank" >https://www.nature.com/articles/s41598-025-16612-2</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41598-025-16612-2" target="_blank" >10.1038/s41598-025-16612-2</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of cervical fluid Ureaplasma species in pregnant women with spontaneous preterm delivery

  • Original language description

    Ureaplasma spp., commonly identified in the vagina/cervix of pregnant women with spontaneous preterm delivery, are the most frequently detected microorganisms in amniotic fluid. To date, 14 U. spp. serotypes have been characterized; however, modern molecular biology methods can distinguish different U. spp genotypes. Considering these factors, a knowledge gap exists regarding the association between U. spp. genotypes and the risk of the ascension of U. spp. from the cervix to the amniotic cavity. To fill this gap, an expanded multilocus sequence-typing scheme of U. spp. was performed to assess the relationship between cervical and amniotic fluid U. spp. in pregnant women with spontaneous preterm delivery. This study included 109 and 69 pregnant women with spontaneous preterm labor (PTL) and preterm prelabor rupture of membranes (PPROM), respectively. U. spp. DNA in cervical fluid was identified in 49% and 55% of the women with PTL and PPROM, respectively. The concurrent presence of U. spp. DNA in amniotic fluid was observed in 17% and 59% of the pregnant women with PTL and PPROM, respectively. Among pregnant women with PTL and PPROM, 38 expanded sequence types of cervical U. spp. were identified. No associations were observed between specific genotypes, subgroups, or clusters of cervical U. spp. and the presence of amniotic fluid U. spp. in pregnant women with spontaneous preterm delivery.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30214 - Obstetrics and gynaecology

Result continuities

  • Project

    <a href="/en/project/EH23_021%2F0008439" target="_blank" >EH23_021/0008439: Biomedical Indicators for Personalized Medicine</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scientific Reports

  • ISSN

    2045-2322

  • e-ISSN

    2045-2322

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    15

  • Pages from-to

    31997

  • UT code for WoS article

    001565399800034

  • EID of the result in the Scopus database

    2-s2.0-105014915896