Primary ventriculitis caused by Streptococcus intermedius – a rare case and challenge with uncertain clinical outcome. Case report

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F25%3A10159689" target="_blank" >RIV/00098892:_____/25:10159689 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/25:73629731
Result on the web
<a href="https://biomed.papers.upol.cz/artkey/bio-202504-0009_primary-ventriculitis-caused-by-streptococcus-intermedius-a-rare-case-and-challenge-with-uncertain-clinical-o.php" target="_blank" >https://biomed.papers.upol.cz/artkey/bio-202504-0009_primary-ventriculitis-caused-by-streptococcus-intermedius-a-rare-case-and-challenge-with-uncertain-clinical-o.php</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2024.029" target="_blank" >10.5507/bp.2024.029</a>

Result language
angličtina
Original language name
Primary ventriculitis caused by Streptococcus intermedius – a rare case and challenge with uncertain clinical outcome. Case report
Original language description
Aims. To present a case of primary ventriculitis in a 53-year-old patient caused by Streptococcus intermedius, emphasizing the rarity of the condition and the challenges in achieving clinical improvement despite targeted therapy. Methods. The patient underwent clinical evaluation, including CT and MRI imaging, as well as CSF analysis. Empirical antibiotic therapy was initiated with cefotaxime and metronidazole, followed by targeted therapy based on CSF culture results. External ventricular drainage was performed surgically. Results. No predisposing factors were identified in the patient. Initial imaging showed no acute changes, but follow-up imaging revealed significant ventricular inflammation. CSF analysis confirmed the presence of Streptococcus intermedius. Despite early and targeted antibiotic therapy, and surgical intervention, the patient’s clinical condition did not improve. Conclusion. This case highlights the rarity of primary ventriculitis caused by Streptococcus intermedius and the challenges in managing it. The lack of clinical improvement despite prompt and targeted treatment underscores the need for further research to develop more effective therapeutic strategies for such infections.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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