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Thromboxane Prostaglandin Receptor Antagonist and Carotid Atherosclerosis Progression in Patients With Cerebrovascular Disease of Ischemic Origin A Randomized Controlled Trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00061525" target="_blank" >RIV/00159816:_____/14:00061525 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/14:#0000839 RIV/00843989:_____/14:E0104979

  • Result on the web

    <a href="http://dx.doi.org/10.1161/STROKEAHA.114.004775" target="_blank" >http://dx.doi.org/10.1161/STROKEAHA.114.004775</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1161/STROKEAHA.114.004775" target="_blank" >10.1161/STROKEAHA.114.004775</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Thromboxane Prostaglandin Receptor Antagonist and Carotid Atherosclerosis Progression in Patients With Cerebrovascular Disease of Ischemic Origin A Randomized Controlled Trial

  • Original language description

    Background and Purpose-Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, asmeasured by common carotid intima-media thickness and carotid plaques. Methods-A substudy was performed among 1141 participants of the aspirin-controlled Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin with Terutroban in Patients with a History of Ischemic Stroke or Transient Ischemic Attack (PERFORM) trial. Common carotid intima-media thickness and carotid plaque occurrence was measured during a 3-year period. Results-Baseline characteristics did not differ between Terutroban (n=592) and aspirin (n=549) treated patients and were similar as in the main study. Mean study and treatment duration were similar (28 and 25 months, respectively). In the Terutroban group, the annualized rate of change in common caroti

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Stroke

  • ISSN

    0039-2499

  • e-ISSN

  • Volume of the periodical

    45

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    2348-2353

  • UT code for WoS article

    000340297300032

  • EID of the result in the Scopus database