"Liberation treatment" for chronic cerebrospinal venous insufficiency in multiple sclerosis: the truth will set you free
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00062695" target="_blank" >RIV/00159816:_____/15:00062695 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/brb3.297" target="_blank" >http://dx.doi.org/10.1002/brb3.297</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/brb3.297" target="_blank" >10.1002/brb3.297</a>
Alternative languages
Result language
angličtina
Original language name
"Liberation treatment" for chronic cerebrospinal venous insufficiency in multiple sclerosis: the truth will set you free
Original language description
BackgroundChronic cerebrospinal venous insufficiency (CCSVI) has recently been introduced as a chronic state of impaired cerebral or cervical venous drainage that may be causally implicated in multiple sclerosis (MS) pathogenesis. Moreover, percutaneoustransluminal angioplasty of extracranial veins termed Liberation treatment has been proposed (based on nonrandomized data) as an alternative therapy for MS. Methods A comprehensive literature search was conducted to identify available published, peer-reviewed, clinical studies evaluating (1) the association of CCSVI with MS, (2) the reproducibility of proposed ultrasound criteria for CCSVI detection (3) the safety and efficacy of Liberation treatment in open-label and randomized-controlled trial (RCT) settings. Results There is substantial heterogeneity between ultrasound case-control studies investigating the association of CCSVI and MS. The majority of independent investigators failed to reproduce the initially reported high prevalenc
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Brain and Behavior
ISSN
2162-3279
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
"e00297"
UT code for WoS article
000349034700002
EID of the result in the Scopus database
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