Perineural spread in pelvic malignancies can be an alternate explanation for pelvic bony metastases rather than hematogenous spread. A report of two cases

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00062973" target="_blank" >RIV/00159816:_____/15:00062973 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s00256-015-2143-3" target="_blank" >http://dx.doi.org/10.1007/s00256-015-2143-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00256-015-2143-3" target="_blank" >10.1007/s00256-015-2143-3</a>

Result language

angličtina

Original language name

Perineural spread in pelvic malignancies can be an alternate explanation for pelvic bony metastases rather than hematogenous spread. A report of two cases

Original language description

We propose that pelvic malignancies can spread to bone and cause bony metastases using nerves as conduits.We reviewed two cases of pelvic malignancy with perineural spread of bladder cancer and prostate cancer. In a patient with prostate cancer, we identified six lesions that were positive on the 11C-choline PET/CTscan and MRI; in a patient with bladder cancer, we identified two lesions positive on the 18F-deoxy- glucose PET/CT scan and MRI. We carefully reviewed the imaging studies, and using established sclerotome maps we identified spinal nerves supplying each of eight pelvic bony lesions. All these spinal nerves showed evidence of tumor infiltration with extension toward the affected bones. We theorize that perineural tumor spread may serve as an additional mechanism of pelvic osseous metastases in pelvic malignancies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Skeletal Radiology

ISSN

0364-2348

e-ISSN

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Volume of the periodical

44

Issue of the periodical within the volume

9

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

1365-1370

UT code for WoS article

000358329600017

EID of the result in the Scopus database

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