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Safety of Statin Pretreatment in Intravenous Thrombolysis for Acute Ischemic Stroke

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00063129" target="_blank" >RIV/00159816:_____/15:00063129 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1161/STROKEAHA.115.010244" target="_blank" >http://dx.doi.org/10.1161/STROKEAHA.115.010244</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1161/STROKEAHA.115.010244" target="_blank" >10.1161/STROKEAHA.115.010244</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Safety of Statin Pretreatment in Intravenous Thrombolysis for Acute Ischemic Stroke

  • Original language description

    Background and Purpose-A recent meta-analysis investigating the association between statins and early outcomes in acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) indicated that prestroke statin treatment was associated with increased risk of 90-day mortality and symptomatic intracranial hemorrhage. We investigated the potential association of statin pretreatment with early outcomes in a large, international registry of AIS patients treated with IVT. Methods-We analyzed prospectively collected data from the Safe Implementation of Treatments in Stroke-East registry (SITS-EAST) registry on consecutive AIS patients treated with IVT during an 8-year period. Early clinical recovery within 24 hours was defined as reduction inbaseline National Institutes of Health Stroke Scale score of GREATER-THAN OR EQUAL TO10 points. Favorable functional outcome at 3 months was defined as modified Rankin Scale scores of 0 to 1. Symptomatic intracranial hemorrhage was diagno

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Stroke

  • ISSN

    0039-2499

  • e-ISSN

  • Volume of the periodical

    46

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    4

  • Pages from-to

    2681-2684

  • UT code for WoS article

    000360919700056

  • EID of the result in the Scopus database