Atopic phenotype associations with rs7927894 inter gene polymorphism on chromosome 11q13.5 in Czech adult patients with atopic dermatitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00064031" target="_blank" >RIV/00159816:_____/15:00064031 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.15761/GOD.1000137" target="_blank" >http://dx.doi.org/10.15761/GOD.1000137</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.15761/GOD.1000137" target="_blank" >10.15761/GOD.1000137</a>
Alternative languages
Result language
angličtina
Original language name
Atopic phenotype associations with rs7927894 inter gene polymorphism on chromosome 11q13.5 in Czech adult patients with atopic dermatitis
Original language description
We did not observe significant differences in genotype distribution and/or allelic frequencies between AD men and women in polymorphism rs792894. But, the CT genotype of polymorphism rs7927894 on chromosome 11q13.5 was more than 4times more frequently observed in AD women with elevated levels of the total IgE above 158 IU/ml. In AD men, a significant association of polymorphism rs7927894 on chromosome 11q13.5 with atopic phenotype/ predisposition was found: the genotypes CC and TT are 6 times more frequent in AD men with other atopic phenotype (asthma, atopic rhinitis) compared to AD men without it. The TT genotype of the polymorphism was 4 times more frequent in men with positive family history of atopic phenotypes.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FO - Dermatology and venereology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů