Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00064254" target="_blank" >RIV/00159816:_____/15:00064254 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3791/53100" target="_blank" >http://dx.doi.org/10.3791/53100</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3791/53100" target="_blank" >10.3791/53100</a>
Alternative languages
Result language
angličtina
Original language name
Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention
Original language description
Rapid endothelialization of cardiovascular stents is needed to reduce stent thrombosis and to avoid anti-platelet therapy which can reduce bleeding risk. The feasibility of using magnetic forces to capture and retain endothelial outgrowth cells (EOC) labeled with super paramagnetic iron oxide nanoparticles (SPION) has been shown previously. But this technique requires the development of a mechanically functional stent from a magnetic and biocompatible material followed by in-vitro and in-vivo testing toprove rapid endothelialization. We developed a weakly ferromagnetic stent from 2205 duplex stainless steel using computer aided design (CAD) and its design was further refined using finite element analysis (FEA). The final design of the stent exhibiteda principal strain below the fracture limit of the material during mechanical crimping and expansion. One hundred stents were manufactured and a subset of them was used for mechanical testing, retained magnetic field measurements, in-vitr
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Jove-Journal of Visualized Experiments
ISSN
1940-087X
e-ISSN
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Volume of the periodical
SEP
Issue of the periodical within the volume
103
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
"e53100"
UT code for WoS article
000364222300031
EID of the result in the Scopus database
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