Safety of intravenous thrombolysis for acute ischemic stroke in specific conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00064391" target="_blank" >RIV/00159816:_____/15:00064391 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1517/14740338.2015.1032242" target="_blank" >http://dx.doi.org/10.1517/14740338.2015.1032242</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1517/14740338.2015.1032242" target="_blank" >10.1517/14740338.2015.1032242</a>
Alternative languages
Result language
angličtina
Original language name
Safety of intravenous thrombolysis for acute ischemic stroke in specific conditions
Original language description
Introduction: Intravenous administration of tissue-type plasminogen activator (IV-tPA) remains the only approved therapy that may reverse neurological deficit in patients with acute ischemic stroke (AIS). During the past 20 years, accumulating real-wordexperience have provided additional information regarding its safety and efficacy in various clinical settings that were originally considered as contraindications for systemic thrombolysis. Areas covered: In this narrative review, we address the safetyof intravenous thrombolysis (IVT) in specific conditions: dissection of the aortic arch of extracranial and intracranial arteries, concomitant presence of unruptured intracranial aneurysms, arteriovenous malformations and dural fistulas, coexisting braintumors as well as in conditions mimicking AIS. The review systematically evaluates the safety of off-label use of IVT and summarizes data from case reports of uncommon complications of systemic thrombolysis administration in the setting
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Expert Opinion On Drug Safety
ISSN
1474-0338
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
20
Pages from-to
845-864
UT code for WoS article
000354541400006
EID of the result in the Scopus database
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