Patient survival, predictive factors and disease course of severe sepsis in Czech intensive care units: a multicentre, retrospective, observational study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00063773" target="_blank" >RIV/00159816:_____/16:00063773 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00089692 RIV/00216208:11140/16:10326686 RIV/00216208:11150/16:10326686 RIV/61989592:15110/16:33156211 and 4 more

Result on the web

<a href="http://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-1195" target="_blank" >http://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-1195</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2015.052" target="_blank" >10.5507/bp.2015.052</a>

Result language

angličtina

Original language name

Patient survival, predictive factors and disease course of severe sepsis in Czech intensive care units: a multicentre, retrospective, observational study

Original language description

Severe sepsis/septic shock is associated with high mortality. In Central Europe, there is a dearth of information on the prevalence and treatment of severe sepsis. The EPOSS (Data-based Evaluation and Prediction of Outcome in Severe Sepsis) project launched in 2011 was aimed at collecting data on patients with severe sepsis/septic shock. Methods: The EPOSS study processes data from the EPOSS project database, and is a retrospective, multicentre, observational study. This included all consecutive patients aged 18 and over who were admitted to participating ICUs from 1 January 2011 to 5 November 2013 and met the inclusion criteria of severe sepsis/septic shock. The primary endpoint was to analyse the relationship between in-hospital mortality (either in ICU or after discharge from ICU) and the type and number of fulfilled diagnostic and treatment interventions during the first 6 h after the diagnosis of severe sepsis/septic shock. Results: The collected dataset involved 1082 patients meeting the criteria of severe sepsis/septic shock. Following data validation, a final dataset of 897 patients was obtained. The average age of the patient group was 64.7 years; mortality at discharge from EPOSS ICUs was 35.5% and from hospital 40.7%. Of the 10 evaluated diagnostic and treatment interventions within the initial 6 hours of identifying severe sepsis/septic shock (i.e. fulfilment of SSC bundles), four or five diagnostic and treatment interventions were administered to 58.4% patients. Combined diagnostic and treatment interventions associated with the lowest in-hospital mortality were: CVP of GREATER-THAN OR EQUAL TO8-12 mm Hg & MAP of GREATER-THAN OR EQUAL TO65 mm Hg & Urine output at GREATER-THAN OR EQUAL TO0.5 mL/kg/h & Lactate of LESS-THAN OR EQUAL TO4.0 mmol/L & Initial lactate measured & Antibiotics in the first hour. ...

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical papers

ISSN

1213-8118

e-ISSN

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Volume of the periodical

160

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

287-297

UT code for WoS article

000379360500017

EID of the result in the Scopus database

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